All the stones sold from 2sculpt are safe: no asbestos, arsenic, radioactivity, or trans-fats. Stones of which to be cautious are sandstone and granite (silica), soapstone (asbestos), and jade and copper (heavy metals). This is not to say that they cannot be sculpted; just be thoughtful of the dust.
You should always wear at least a paper mask (to minimize lung congestion) and safety glasses. If you are using power tools and therefore creating a lot of dust you need ear protection and should have on a respirator. Whereas a paper mask catches about 40% of the dust, a double respirator labeled as P100 will provide about 99% protection (less than $20 for a 3M half respirator). Gel bicycle gloves without the fingers are my favorite for vibration. There are more elaborate anti-vibration gloves that secure the wrist to minimize carpel tunnel damage.